| Объем | 100 мкл |
| Синонимы | CDH1, CDHE, UVO |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P12830 |
| Иммуноген | Peptide sequence around aa.864~868(E-W-G-N-R) derived from Human E-Cadherin. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin a-E/beta-7. E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production. <br/><br/>Baki L.et.al(2001)Proc. Natl. Acad. Sci. U.S.A. 98:2381-2386<br/>Makagiansar I.T.et.al(2002)J. Biol. Chem. 277:16002-16010<br/>Agiostratidou G. (2006)J. Neurochem. 96:1182-1188<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Developmental biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extract from MCF-7 and HT29 cells using E-Cadherin(CD324) Antibody
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Наименование: CDH1 Antibody.