| Объем | 100 мкл |
| Синонимы | CDC42-binding protein kinase beta, CDC42BPB, EC 2.7.11.1, MRCK-beta, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y5S2 |
| Иммуноген | Synthesized peptide derived from internal of human MRCKB. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates PPP1R12A.<br/><br/>Nakajima D., DNA Res. 9:99-106(2002).<br/>Olsen J.V., Cell 127:635-648(2006).<br/>Hirosawa M., DNA Res. 6:329-336(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from COLO cells, using MRCKB antibody.
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Immunohistochemistry analysis of paraffin-embedded human brain tissue using MRCKB antibody.
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Наименование: CDC42BPB Antibody.