| Объем | 100 мкл |
| Синонимы | CCAAT displacement protein, CDP, Cut-like 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P39880 |
| Иммуноген | Synthesized peptide derived from N-terminal of human CUTL1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor, binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Binds to the TH enhancer, may require the basic helix-loop-helix protein TCF4 as a coactivator By similarity.<br/><br/>Neufeld E.J., Nat. Genet. 1:50-55(1992).<br/>Gloeckner G., Genome Res. 8:1060-1073(1998).<br/>Rong Zeng W., Gene 241:75-85(2000). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from K562 cells, using CUTL1 antibody.
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Наименование: CUX1 Antibody.