| Объем | 100 мкл |
| Синонимы | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, EC 3.1.3.16, Nuclear LIM interactor-interacting factor 3, NLI-interacting factor 3, NLI-IF |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9GZU7 |
| Иммуноген | Synthesized peptide derived from N-terminal of human CTDSP1. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.<br/><br/>Marquet S., Mamm. Genome 11:755-762(2000).<br/>Yeo M., J. Biol. Chem. 278:26078-26085(2003).<br/>Hillier L.W., Nature 434:724-731(2005)<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CTDSP1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 antibody.
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Наименование: CTDSP1 Antibody.