| Объем | 100 мкл |
| Синонимы | CD5R, CD5R1, CDK5 activator 1, CDK5R, Cyclin-dependent kinase 5 activator 1 precursor |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q15078 |
| Иммуноген | Synthesized peptide derived from internal of human CDK5R1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 |
| Примечание | p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.<br/><br/>Tsai L.-H., Nature 371:419-423(1994).<br/>Patrick G.N., Nature 402:615-622(1999).<br/>Kesavapany S., J. Neurosci. 24:4421-4431(2004). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cell biology,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from rat brain cells, using CDK5R1 antibody.
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Immunofluorescence analysis of HeLa cells, using CDK5R1 antibody.
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Наименование: CDK5R1 Antibody.