| Объем | 50 мкл |
| Синонимы | apoptotic chromatin condensation inducer 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9UKV3 |
| Иммуноген | Synthetic peptide of human ACIN1 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Примечание | Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cell biology,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA964463(ACIN1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA964463(ACIN1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane 1-2: K562 cells, 231 cells, Primary antibody: CSB-PA964463(ACIN1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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