| Объем | 100 мкл |
| Синонимы | Dual specificity protein kinase CLK4, EC 2.7.12.1, CDC-like kinase 4, CLK4, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9HAZ1 |
| Иммуноген | Synthesized peptide derived from internal of human CLK4. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates SRSF1 and SRSF3. Required for the regulation of alternative splicing of MAPT/TAU. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells.<br/><br/>Schultz J., Genomics 71:368-370(2001).<br/>McNally T., Protein Sci. 12:1562-1566(2003).<br/>Kantham L., Biochem. Biophys. Res. Commun. 304:125-129(2003).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT-29 cells, using CLK4 antibody.
 |
| | |
Наименование: CLK4 Antibody.