CCNF AntibodyСпецификация| Объем | 100 мкл | | Синонимы | FBX1, FBXO1, F-box only protein 1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P41002 | | Иммуноген | Synthesized peptide derived from human Cyclin F. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication.<br/><br/>Tsz Kan Fung, J. Biol. Chem., Sep 2002, 277: 35140 - 35149.<br/>Michael T. Tetzlaff, Mol. Cell. Biol., Mar 2004, 24: 2487 - 2498.<br/>Cain H. Yam, Mol. Cell. Biol., Jan 1999, 19: 635 - 645.<br/>Michael T. Tetzlaff, PNAS, Mar 2004, 101: 3338 - 3345.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Cyclin F antibody.
 | Western blot analysis of extracts from HeLa cells, using Cyclin F antibody.
 | Western blot analysis of extracts from HeLa cells (Lane 2), A549 cells (Lane 3) and HepG2 cells (Lane 4), using Cyclin F antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: CCNF Antibody.