CHRNA10 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ach10, cholinergic receptor, nicotinic, alpha 10, chrna10 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9GZZ6 | | Иммуноген | Synthesized peptide derived from C-terminal of human CHRNA10. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.<br/><br/>Sgard F., Mol. Pharmacol. 61:150-159(2002).<br/>Lustig L.R., Genomics 73:272-283(2001).<br/>Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Neuroscience,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from A549 cells, COLO cells, HeLa cells and 293 cells, using CHRNA10 antibody.
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Наименование: CHRNA10 Antibody.