| Объем | 100 мкл |
| Синонимы | ICE-like apoptotic protease 6 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P55211 |
| Иммуноген | Peptide sequence around aa.301~305 (T-S-P-E-D) derived from Caspase 9 |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP). Isoform 2 lacks activity is an dominant-negative inhibitor of caspase-9.<br/><br/>Zou, H. et al. (1999) J. Biol. Chem. 274, 11549-11556.<br/>Deveraux, Q. L. et al. (1998) EMBO J. 17, 2215-2223.<br/>Li, P. et al. (1997) Cell 91, 479-489.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Области исследований | Cancer,Cell biology,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 and Hela cells using Caspase 9 Antibody.
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Наименование: CASP9 Antibody.