BBS1 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Bardet-Biedl syndrome 1 protein (BBS2-like protein 2), BBS1, BBS2L2
Клональность	Polyclonal Antibody
Организм	Human
uniprot	Q8NFJ9
Иммуноген	Recombinant Human Bardet-Biedl syndrome 1 protein (217-417AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Bardet-Biedl syndrome 1 protein
Области исследований	Neuroscience
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA836736LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: BBS1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).