ASPSCR1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ASPL, RCC17, TUG, UBXD9, UBXN9 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9BZE9 | | Иммуноген | Peptide sequence around aa.303 ~307(P-Q-Q-E-Q) derived from Human ASPSCR1. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:1000 | | Примечание | Tug (Tether containing UBX domain for GLUT4), also known as ASPL, ASPSCR1, RCC17, UBXD9, UBXN9, was first identified as a chromosomal translocation partner for TFE3 in patients with Alveolar soft part sarcoma and contains an UBX-like domain in its C-terminal region. Tug is found to tether GLUT4 in intracellular vesicles and to release GLUT4 for cell surface translocation upon insulin stimulation . Stable Tug depletion or expression of a dominant negative form stimulates GLUT4 redistribution.<br/><br/>Ladanyi, M. et al. (2001) Oncogene 20, 48-57. <br/>Bogan, J.S. et al. (2003) Nature 425, 727-33. <br/>Yu, C. et al. (2007) J Biol Chem 282, 7710-22. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HL60 cells using ASPSCR1 Antibody.
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Наименование: ASPSCR1 Antibody.