| Объем | 100 мкл |
| Синонимы | Aryl hydrocarbon receptor nuclear translocator, Dioxin receptor, nuclear translocator, HIF-1 beta, Hypoxia-inducible factor 1 beta |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P27540 |
| Иммуноген | Synthesized peptide derived from internal of human ARNT. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.<br/><br/>Hoffman E.C., Science 252:954-958(1991).<br/>Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995).<br/>Nguyen T.A., Arch. Biochem. Biophys. 367:250-257(1999).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Cardiovascular,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, using ARNT antibody.
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Наименование: ARNT Antibody.