ARIH2 AntibodyСпецификация| Объем | 50 мкг | | Синонимы | E3 ubiquitin-protein ligase ARIH2 (ARI-2) (Protein ariadne-2 homolog) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein), ARIH2, ARI2 TRIAD1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O95376 | | Иммуноген | Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (43-360AA) | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC, Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200 | | Примечание | E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates 'Lys-6', 'Lys-48'-and 'Lys-63'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006). | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | >95%, Protein G purified | | Абревеатура | E3 ubiquitin-protein ligase ARIH2 | | Области исследований | Epigenetics and Nuclear Signaling, Cell biology | | Ссылка на страницу на сайте производителя | ссылка | Western Blot
Positive WB detected in: HEK293 whole cell lysate, Hela whole cell lysate, Jurkat whole cell lysate, Mouse heart tissue, Mouse liver tissue, Mouse brain tissue
All lanes: ARIH2 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 58 kDa
Observed band size: 58 kDa
 | Immunohistochemistry of paraffin-embedded human lymph node tissue using CSB-PA002069LA01HU at dilution of 1:100
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Наименование: ARIH2 Antibody.