| Объем | 50 мкл |
| Синонимы | Arachidonate 5-lipoxygenase |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P09917 |
| Иммуноген | Fusion protein of human ALOX5 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, IHC,ELISA:1:500-1:5000, IHC:1:50-1:150 |
| Примечание | This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Cancer,Cardiovascular,Metabolism,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA043268(ALOX5 Antibody) at dilution 1/50. (Original magnification: ?200)
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The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA043268(ALOX5 Antibody) at dilution 1/50. (Original magnification: ?200)
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Наименование: ALOX5 Antibody.