| Объем | 100 мкл |
| Синонимы | Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (Multisynthase complex auxiliary component p43) [Cleaved into: Endothelial monocyte-activating polypeptide 2 (EMAP-2) (Endothelial monocyte-activating polypeptide II) (EMAP-II) (Small inducible cytokine subfamily E member 1)], AIMP1, EMAP2 SCYE1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q12904 |
| Иммуноген | Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (25-180AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, IP, Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IP:1:200-1:2000 |
| Примечание | Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Cell biology, Tags & Cell Markers, Immunology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 antibody at 2µg/ml + HepG2 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 35, 38 kDa
Observed band size: 35 kDa
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Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA618638DSR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA618638DSR1HU at dilution of 1:100
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Наименование: AIMP1 Antibody.