| Объем | 50 мкл |
| Синонимы | Activin receptor type-1C (EC 2.7.11.30) (Activin receptor type IC) (ACTR-IC) (Activin receptor-like kinase 7) (ALK-7), ACVR1C, ALK7 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q8NER5 |
| Иммуноген | Recombinant Human Activin receptor type-1C protein (22-113AA) |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
| Примечание | Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Epigenetics and Nuclear Signaling, Cancer, Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: ACVR1C antibody at 4µg/ml
Lane 1: Mouse brain tissue
Lane 2: HepG2 whole cell lysate
Lane 3: Hela whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 38, 47, 50 kDa
Observed band size: 55 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA854112ESR1HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA854112ESR1HU at dilution of 1:100
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