ACTN4 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | actinin, alpha 4 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O43707 | | Иммуноген | Fusion protein of human ACTN4 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 | | Примечание | Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA070925(ACTN4 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA070925(ACTN4 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
 | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane 1-4: Lovo cells, mouse kidney tissue, 231 cells, hepG2 cells, Primary antibody: CSB-PA070925(ACTN4 Antibody) at dilution 1/485, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: ACTN4 Antibody.