| Объем | 100 мкл |
| Синонимы | c-myc |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P01106 |
| Иммуноген | Peptide sequence around phosphorylation site of threonine 58 (L-P-T(p)-P-P) derived from Human Myc. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse, Rat |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes.<br/><br/>Jin Z, et al. (2004) J Biol Chem. 279(38): 40209-40219.<br/>Welcker M, et al. (2004) Proc Natl Acad Sci U S A. 101(24): 9085-9090.<br/>Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702.<br/>Blackwood E M, et al. (1991) Science. 251:1211-1217.<br/>Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182.<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Thr58 |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela cells using Myc(Phospho-Thr58) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Myc(Phospho-Thr58) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Myc(Phospho-Thr58) Antibody.