Rabbit Anti Human TPM1 PolyClonal Antibody

Спецификация

Объем	100 мкл (100 мкг)
Синонимы	TPM1,CMH3, TMSA, CMD1Y, C15orf13, HTM-alpha
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P09493
Иммуноген	Recombinant protein of human TPM1
Источник	Rabbit
Видовая специфичность	Human, Mouse, Rat
Применение	ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200
Примечание	Tropomyosin-1 (TPM1) belongs to the high molecular weight members of tropomyosin family. The protein exists in an alpha-helical coiled-coil conformation and binds multiple acting monomers in a tight manner to stabilize and regulate the actin filament. Tropomyosins fullfill functions in muscle and non-muscle cells. In muscle cells, tropomyosins associate with the troponin complex and play a central role in the calcium-dependent regulation of striated muscle contraction in vertebrates. In non-muscle cells, tropomyosins are implicated in the formation and stabilization of cytoskeletal actin filaments to ensure normal cellular processes. Mutations of tropomysin-1 have been reported as a cause of dilated cardiac myopathies. Tropomyosin-1 also functions as a tumor suppressor, and many malignant tumors demonstrate downregulation of tropomyosin-1 expression. Tropomyosin-1 is phosphorylated at Ser283 through the Erk/DAPK pathway, which promotes stress fiber formation in response to oxidative stress.
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Non-conjugated
Буффер	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Форма	liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	Affinity purification
Области исследований	Cardiovascular,Signal transduction
Ссылка на страницу на сайте производителя	ссылка
Western blot analysis of HT-1080 cell and heart cell lysate using TPM1 antibody.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкл (100 мкг)
	Кат. номер:	CSB-PA024104KA01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Rabbit Anti Human TPM1 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке).