| Rabbit Anti Human RUNX1 PolyClonal AntibodyСпецификация| Объем | 100 мкл (100 мкг) |  | Синонимы | RUNX1, AML1, AML1-EVI-1, AMLCR1, CBFA2, EVI-1, PEBP2Ab |  | Клональность | Polyclonal Antibody |  | Организм | Human |  | uniprot | Q01196 |  | Иммуноген | A synthetic peptide of human RUNX1 |  | Источник | Rabbit |  | Видовая специфичность | Human, Mouse, Rat |  | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 |  | Примечание | AML1 (also known as Runx1, CBFA2, and PEBP2alphaB) is a member of the core binding factor (CBF) family of transcription factors. It is required for normal development of all hematopoietic lineages. AML1 forms a heterodimeric DNA binding complex with its partner protein CBFbeta and regulates the expression of cellular genes by binding to promoter and enhancer elements. AML1 is commonly translocated in hematopoietic cancers: chromosomal translocations include t(8,21) AML1-ETO, t(12,21) TEL-AML, and t(8,21) AML-M2. Phosphorylation of AML1 on several potential serine and threonine sites, including Ser249, is thought to occur in an Erk-dependent manner. |  | Клональность1 | Polyclonal |  | Изотип | IgG |  | Коньюгат | Non-conjugated |  | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |  | Форма | liquid |  | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |  | Метод очистки | Affinity purification |  | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Developmental biology,Stem cells |  | Ссылка на страницу на сайте производителя | ссылка |  | Western blot analysis of extracts of various cell lines, using RUNX1 antibody. 
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 Информация для заказа| Область использования: | Производство: | Cusabio |  | Метод: |  |  | Объем: | 100 мкл (100 мкг) |  | Кат. номер: | CSB-PA020592KA01HU |  | Цена (с НДС 20%): | по запросу | В корзину  |  |  Наименование: Rabbit Anti Human RUNX1 PolyClonal Antibody. Примечание: дополнительная информация (на английском языке).
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