Антитела Rabbit anti-human Glutamate carboxypeptidase 2 polyclonal Antibody

Rabbit anti-human Glutamate carboxypeptidase 2 polyclonal Antibody

Immunogen: Recombinant human Glutamate carboxypeptidase 2 protein
Raised in: Rabbit
Species Reactivity: Human
Tested applications: ELISA, WB, IHC
Application notes:
Relevance: Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Isoform PSM-4 and isoform PSM-5 would appear to be physiologically irrelevant. Involved in prostate tumor progression.Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC.
Clonality: Polyclonal
Isotype: IgG
Purity: Caprylic Acid Ammonium Sulfate Precipitation purified
Conjugate: Non-conjugated
Stroage Buffer: Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form: Liquid
Stroage: Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze.
References: [1]"Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen."IsraeliR.., Powell C.T., Fair W.R., Heston W.D.W.Cancer Res. 53:227-230(1993) [2]"Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression."Su S.L., Huang I.-P., Fair W.R., Powell C.T., Heston W.D.W. Cancer Res. 55:1441-1443(1995) [3]"Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene."O'Keefe D.S., Su S.L., Bacich D.J., Horiguchi Y., Luo Y., Powell C.T., Zandvliet D., Russell P.J., Molloy P.L., Nowak N.J., Shows T.B., Mullins C., Vonder Haar R.A., Fair W.R., Heston W.D.W. Biochim. Biophys. Acta 1443:113-127(1998)
Images:
Alias : GIG27,FOLH, NAALAD1, PSM, PSMA,FOLH1,Cell growth-inhibiting gene 27 protein,Folate hydrolase 1,Folylpoly-gamma-glutamate carboxypeptidase,FGCP,Glutamate carboxypeptidase II,GCPII,Membrane glutamate carboxypeptidase,mGCP,N-acetylated-alpha-linked acidic dipeptidase I,NAALADase I,Prostate-specific membrane antigen,PSM,PSMA,Pteroylpoly-gamma-glutamate carboxypeptidase.

Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:
	Объем:	100 мкг
	Кат. номер:	CSB-PA11727A0Rb
Цена (с НДС 20%):	по запросу	В корзину
Наименование: Антитела Rabbit anti-human Glutamate carboxypeptidase 2 polyclonal Antibody / Rabbit anti-human Glutamate carboxypeptidase 2 polyclonal Antibody. Примечание: дополнительная информация (на английском языке).