IRF-7 Antibody (G-8) is a mouse monoclonal IgG2a
- IRF-7 Antibody (G-8) is a mouse monoclonal IgG2a provided at 200 µg/ml
- raised against amino acids 1-246 of IRF-7 of human origin
- recommended for detection of IRF-7 of human origin by WB, IP, PAR, ELISA
- TransCruz reagent for Gel Supershift and ChIP applications, sc-74472 X, 200 µg/0.1 ml
- See 9 citations for IRF-7 Antibody (G-8)
Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-å and ∫) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-å and interferon-∫ genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3© p48 and IFN consensus sequence-binding protein (ICSBP). Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-74472 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: IRF-7 Antibody (G-8) is a mouse monoclonal IgG2a.
Примечание: SQ Category: Primary Antibodies,
Species: human,
Host Origin: human,
Applications: WB, IP, IF, IHC(P), ELISA,
UNSPSC: 12352203,
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