GPR91 Antibody (H-80) is a rabbit polyclonal IgG
- GPR91 Antibody (H-80) is a rabbit polyclonal IgG provided at 200 µg/ml
- epitope corresponding to amino acids 86-165 mapping within an internal region of GPR91 of human origin
- recommended for detection of GPR91 of mouse, rat and human origin by WB, IP, IF and ELISA
- See 1 citations for GPR91 Antibody (H-80)
GPR91 (formerly known as P2U2 ) is a G protein-coupled, dicarboxylic acid succinate receptor. It has a high level of expression in the kidney, predominantly in the proximal tubules, and localizes to the plasma membrane. It has also been found at low levels in the liver and the spleen. GPR91 functions as a citric acid cycle intermediate succinate receptor. Two signaling pathways result from GPR91 activation, the pertussis-toxin-sensitive Gi/Go pathway and the pertussis-toxin-insensitive Gq pathway. Four amino acid residues are necessary for GPR91 activation by succinate, Arg 99, His 103, Arg 252, and Arg 281. GPR91 plays an important role in the succinate-induced hypertensive effect and may be involved in renovascular hypertension, a disease linked to diabetes, renal failure, and atherosclerosis. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 200 мкг/мл | | Кат. номер: | sc-50466 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: GPR91 Antibody (H-80) is a rabbit polyclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: m, r, h,
Host Origin: human,
Applications: WB, IP, IF, ELISA,
UNSPSC: 12352203,
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