DC-SIGN Antibody (5D7) is a mouse monoclonal IgG
- DC-SIGN Antibody (5D7) is a mouse monoclonal IgG provided at 100 µg/ml
- raised against a peptide corresponding to amino acids near the C-terminus of DC-SIGN of human origin
- recommended for detection of DC-SIGN of human origin by WB, IP, IF and IHC(P)
- See 4 citations for DC-SIGN Antibody (5D7)
Dendritic cells (DCs) are antigen-presenting immune system cells that are present on peripheral mucosal tissues and migrate to lymphoid tissues. DC-SIGN (DC-specific ICAM-3 grabbing nonintegrin) is a type II membrane protein that is exclusively expressed by DCs. DC-SIGN, also designated CD209, binds to ICAM-3 to mediate the initial interaction between DCs and resting T cells through the immunological synapse. The DCs that are present in the initial sites of HIV-1 infection capture HIV-1 through DC-SIGN, which then facilitates the migration of DCs to areas of T cell-rich secondary lymphoid organs, where it promotes efficient trans HIV-1 infection of those T cells. DC-SIGN functions to transport HIV-1 from exposed mucosal surfaces to a lymphoid compartment. Информация для заказа| Область использования: | Производство: | Santa Cruz | | Метод: | | | Объем: | 100 µg/ml | | Кат. номер: | sc-65892 | | Цена (с НДС 20%): | по запросу | В корзину  | Наименование: DC-SIGN Antibody (5D7) is a mouse monoclonal IgG.
Примечание: SQ Category: Primary Antibodies,
Species: human,
Host Origin: human,
Applications: WB, IP, IF, IHC(P),
UNSPSC: 12352203,
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