Генетические заболевания

Список публикаций по применению технологии x-MAP

• HLA-типирование
• Анализ профиля экспрессии генов
• Биосинтез белка
• Генетические заболевания
• Генотипирование
• Заболевания, вызванные инфекционными молекулами
• Защита от биологического оружия / Экология
• Иммунодиагностика
• Технология

Amos JA, Bridge-Cook P, Ponek V, Jarvis MR, 2006, A universal array-based multiplexed test for cystic fibrosis carrier screening.  Expert Rev Mol Diagn., 6(1):15-22

Benayed R, Gharani N, Rossman I, Mancuso V, Lazar G, Kamdar S, Bruse SE, Tischfield S, Smith BJ, Zimmerman RA, Dicicco-Bloom E, Brzustowicz LM, Millonig JH, 2005, Support for the homeobox transcription factor gene ENGRAILED 2 as an autism spectrum disorder susceptibility locus.  Am J Hum Genet., 77(5):851-68

Bortolin S, Black M, Modi H, Boszko I, Kobler D, Fieldhouse D, Lopes E, Lacroix JM, Grimwood R, Wells P, Janeczko R, Zastawny R, 2004, Analytical validation of the tag-it high-throughput microsphere-based universal array genotyping platform: application to the multiplex detection of a panel of thrombophilia-associated single-nucleotide polymorphisms.  Clin Chem, 50: 2028-2036

Colinas RJ, Bellisario R, Pass KA, 2000, Multiplexed genotyping of beta-globin variants from PCR-amplified newborn blood spot DNA by hybridization with allele-specific oligodeoxynucleotides coupled to an array of fluorescent microspheres.  Clinical Chemistry, 46: 996-998

Dunbar SA, Jacobson JW, 2000, Application of the Luminex LabMAP in rapid screening for mutations in the cystic fibrosis transmembrane conductance regulator gene: A pilot study.  Clinical Chemistry, 46: 1498-1500

Dunbar SA, Jacobson JW, 2005, Rapid screening for 31 mutations and polymorphisms in the cystic fibrosis transmembrane conductance regulator gene by Luminex xMAP suspension array.  Methods Mol Med., 114:147-71

Edelmann L, Hashmi G, Song Y, Han Y, Kornreich R, Desnick RJ, 2004, Cystic fibrosis carrier screening: Validation of a novel method using BeadChip technology.  Genet Med, 6(5):431-8

Hadd AG, Brown JT, Andruss BF, Ye F, WalkerPeach CR, 2005, Adoption of array technologies into the clinical laboratory.  Expert Review of Molecular Diagnostics, 5(3):409-420

Hadd AG, Laosinchai-Wolf W, Novak CR, Badgett MR, Isgur LA, Goldrick M, Walkerpeach CR, 2004, Microsphere Bead Arrays and Sequence Validation of 5/7/9T Genotypes for Multiplex Screening of Cystic Fibrosis Polymorphisms.  Journal of Molecular Diagnostics, 6: 348-355

Jakupciak JP, Wang W, Barker PE, Srivastava S, Atha DH, 2003, Analytical validation of telomerase activity for cancer early detection - TRAP/PCR-CE and hTERT mRNA quantification assay for high-throughput screening of tumor cells  JOURNAL OF MOLECULAR DIAGNOSTICS, Vol. 6, No. 3

Johnson SC, Marshall DJ, Harms G, Miller CM, Sherrill CB, Beaty EL, Lederer SA, Roesch EB, Madsen G, Hoffman GL, Laessig RH, Kopish GJ, Baker MW, Benner SA, Farrell PM, Prudent JR, 2004, Multiplexed genetic analysis using an expanded genetic alphabet.  Clinical Chemistry, 50: 2019-2027

Krafft AE, Lichy JH, 2005, Time-motion analysis of 6 cystic fibrosis mutation detection systems.  Clin Chem, 51(7):1116-22

Lowe M, Spiro A, Zhang YZ, Getts R, 2004, Multiplexed, particle-based detection of DNA using flow cytometry with 3DNA dendrimers for signal amplification.  Cytometry, 60A: 135-144

McWilliams R, Highsmith WE, Rabe KG, de Andrade M, Tordsen LA, Holtegaard LM, Petersen GM, 2005, Cystic fibrosis transmembrane regulator gene carrier status is a risk factor for young onset pancreatic adenocarcinoma.  Gut, 54(11):1661-2

Orloff MS, Iyengar SK, Winkler CA, Goddard KA, Dart RA, Ahuja TS, Mokrzycki M, Briggs WA, Korbet SM, Kimmel PL, Simon EE, Trachtman H, Vlahov D, Michel DM, Berns JS, Smith MC, Schelling JR, Sedor JR, Kopp JB, 2005, Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population.  Physiol Genomics, 21(2):212-21

Pickering JW, McMillin GA, Gedge F, Hill HR, Lyon E, 2004, Flow cytometric assay for genotyping Cytochrome P450 2C9 and 2C19: Comparison with a microelectronic DNA array.  Am J Pharmacogenomics, 4: 199-207

Strom CM, Janeczko RA, Anderson B, Redman J, Quan F, Buller A, McGinniss MJ, Sun WM, 2005, Technical validation of a multiplex platform to detect thirty mutations in eight genetic diseases prevalent in individuals of Ashkenazi Jewish descent.  Genet Med, 7(9):633-9

Titus B, Frierson HF Jr, Conaway M, Ching K, Guise T, Chirgwin J, Hampton G, Theodorescu D, 2005, Endothelin axis is a target of the lung metastasis suppressor gene RhoGDI2.  Cancer Res, 65(16):7320-7

Ugozzoli LA, 2004, Multiplex assays with fluorescent microbead readout: a powerful tool for mutation detection.  Clinical Chemistry, 50: 1963-1965

Wallace J, Zhou Y, Usmani GN, Reardon M, Newburger P, Woda B, Pihan G, 2003, BARCODE-ALL: Accelerated and cost effective genetic risk-stratification in acute leukemia using spectrally addressable liquid bead microarrays.  Leukemia, 17: 1404-1410