GAP-43 Antibody (B-5)

GAP-43 (B-5)

• GAP-43 Antibody (B-5) is a mouse monoclonal IgG₁ (kappa light chain) provided at 200 µg/ml
• raised against amino acids 1-100 mapping at the N-terminus of GAP-43 of human origin
• GAP-43 Antibody (B-5) is recommended for detection of axonal membrane protein GAP-43 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
• GAP-43 Antibody (B-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
• also available conjugated to Alexa Fluor^® 488, Alexa Fluor^® 546, Alexa Fluor^® 594 or Alexa Fluor^® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
• also available conjugated to Alexa Fluor^® 680 or Alexa Fluor^® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR^®Odyssey^®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
• See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
• Contact our Technical Service Department (or your local Distributor) for more information on how to receive a 

GAP-43 (growth associated protein 43, B-50, PP46, calmodulin-binding protein P-57, neuromodulin, neuron growth-associated protein 43, protein F1 is a crucial component for regenerative response in the nervous system. It is present at high levels in neuronal growth cones during development and axonal regeneration. GAP-43 is normally produced by neurons during developmental growth and axonal regeneration, but it is also expressed in specific regions of the normal adult nervous system. The neuron-specific Elav/Hu family member, HuD, interacts with and stabilizes GAP-43 mRNA in developing neurons and leads to increased levels of GAP-43 protein. Heterozygous GAP-43 knockout mice with GAP-43 levels reduced by one-half dipslay significant memory impairments in cued conditioning or on tests of nociceptive or auditory perception.

 

 

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

 

Информация для заказа

Область использования: Антитела для исследований в области нейробиологии для вестерн-блоттинга Антитела для исследований в области нейробиологии для иммунопреципитации Антитела для исследований в области нейробиологии для иммунофлуоресценции Нейробиология Первичные антитела и конъюгаты	Производство:	Santa Cruz
	Метод:
	Объем:	200 мкг/мл
	Кат. номер:	sc-17790
Цена (с НДС 20%):	по запросу	В корзину
Наименование: GAP-43 Antibody (B-5) / GAP-43 (B-5). Примечание: SQ Category: Primary Antibodies, Species: m, r, h, Host Origin: human, Applications: WB, IP, IF, IHC(P), ELISA, UNSPSC: 12352203, datasheet