Rabbit Anti Human NCF2 PolyClonal AntibodyСпецификация| Объем | 100 мкл (100 мкг) | | Синонимы | NCF2,FLJ93058,NCF-2,NOXA2,P67-PHOX,P67PHOX | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P19878 | | Иммуноген | Recombinant protein of human NCF2 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:2000, IHC:1:50-1:200 | | Примечание | The phagocytic NADPH oxidase is a multiprotein enzyme that catalyzes the reduction of oxygen to superoxide in response to pathogenic invasion. The NADPH oxidase consists of 6 subunits, including the membrane-bound p91 phox and p22 phox heterodimers (also known as cytochrome b558), the cytosolic complex of p40phox, p47phox and p67phox, and the small GTPase Rac2. Activation of NADPH oxidase is initiated by cytosolic complex phosphorylation, which induces a conformational change that leads to the translocation of the cytosolic complex to the membrane and formation of an active enzyme with cytochrome b558. Defects in p47phox, often resulting from recombination between p47phox and a nearby homologous pseudogene, cause chronic granulomatous disease. Elevated oxidative stress due to increased myocardial NADPH oxidase activity may be a contributing factor in heart failure.p67phox appears to coordinate assembly of NAPDH oxidase as it associates with multiple subunits as well as the alpha subunit of heterotrimeric G proteins. Mutations in the corresponding p67phox gene are also associated with a form of autosomal recessive chronic granulomatous disease. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Affinity purification | | Области исследований | Others | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of THP1 cell and spleen cell lysate using NCF2 antibody.
 | | | |
Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | | | Объем: | 100 мкл (100 мкг) | | Кат. номер: | CSB-PA015528KA01HU | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Rabbit Anti Human NCF2 PolyClonal Antibody.
Примечание: дополнительная информация (на английском языке). |
|
